Thiazolo[5,4‐ <i>f</i> ]quinoxalines, Oxazolo[5,4‐ <i>f</i> ]quinoxalines and Pyrazino[ <i>b,e</i> ]isatins: Synthesis from 6‐Aminoquinoxalines and Properties

نویسندگان

چکیده

Oxazolo[5,4-f]quinoxalines, thiazolo[5,4-f]quinoxalines and pyrazino[b,e]isatins were all obtained from 5-iodo-6-aminoquinoxalines. While the first two families synthesized by nitrogen functionalization subsequent copper-catalyzed cyclization, latter was Sonogashira coupling, alkyne hydration, oxidative cyclization. Most of polycycles evaluated in biological tests.

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ژورنال

عنوان ژورنال: European Journal of Organic Chemistry

سال: 2021

ISSN: ['1434-193X', '1099-0690']

DOI: https://doi.org/10.1002/ejoc.202100362